Clinical Results Our Sponsors Have Published
Validated Claim Support has conducted clinical studies for hundreds of personal care, device, and nutritional supplement companies. We take confidentiality very seriously, and we are proud when our sponsors choose to publish their clinical results.
The studies below are published sets of clinical results and summaries. If you would like your study to be part of our case studies, please reach out to our business development team. We are happy to collaborate when it is mutually beneficial.
Case study: filtered showerhead
Jolie: Beauty Starts With Clean Water, a 4-Week Showerhead Clinical Study
Jolie is an unusual beauty and personal care company that built its positioning around a simple idea: “Beauty Starts With Clean Water.” Instead of only explaining the chemistry of filtered water, Jolie set out to show consumers how their hair and skin could benefit from cleaner water, using Validated Claim Support data.
Protocol purpose: To determine whether regular use of the Jolie Filtered Showerhead would improve skin hydration, barrier function, pH levels, and the appearance of redness, dryness, texture, complexion, and overall skin health.
Participants: 32, ages 23 to 69, various races, mostly female
Duration: 4 weeks, with evaluations at baseline, 2 weeks, and 4 weeks
Principal investigator: Anna Hardy
Study site: Validated Claim Support, Teaneck, NJ
Study commencement: May 2025
Key test parameters:
- Objective instrumentation: Corneometer (hydration), Vapometer (barrier function and TEWL), and pH meter
- Expert grading, participant questionnaires, and clinical photography
- Skin pH (normal range maintenance), hydration improvement, and skin barrier function improvement
Highlighted claims:
- Statistically significant improvement in skin barrier function, dryness, and redness over 4 weeks
- 100% of participants reported an overall improvement in skin health
- 63% and 50% reported noticing less acne and less eczema, respectively
- By week 2, users responded favorably to 90% of experience-related questions, and by week 4 that reached 100%
Outcomes: Participants using the Jolie Filtered Showerhead saw measurable improvements in skin hydration and barrier function, supported by both objective instrumentation and self-reported results. The study supports a connection between filtered water and healthier skin, positioning consistent Jolie use as a foundational step toward improved skin health rather than a cure for specific dermatological conditions. Jolie used clinical data to substantiate claims most beauty brands only make anecdotally.
The Validated difference: VCS works as an objective, clinical-first laboratory that understands the difference between medical device claims and cosmetic claims. The data connected consumer perception with objective, clinically graded endpoints.
Case study: eye cream
Revision Skincare: A 12-Week Study Evaluating the Efficacy of an Eye Cream
Revision Skincare takes a detailed, clinically focused approach to formulation, summed up in its “No shortcuts. No compromises.” ethos. Because Revision's market position and distribution strategy rely on validated scientific claim support data, VCS was selected as the research site for this clinical study.
Protocol purpose: This single-center, open-label clinical study assessed the efficacy and tolerance of a topical eye cream used over 12 weeks. Its primary goals were:
- To evaluate the eye cream's effect on under-eye dark circles, under-eye puffiness, fine lines and wrinkles, and the overall appearance of the periorbital area, using investigator clinical grading, chromameter, VISIA clinical photography, and a subjective questionnaire at baseline and weeks 4, 8, and 12
- To evaluate the effect on under-eye blood flow using laser Doppler at baseline and weeks 8 and 12
- To assess objective and subjective tolerability (dryness, erythema, edema, burning, stinging, peeling, and itching) at each timepoint
Participants: Healthy women aged 35 to 60, Fitzpatrick skin types I to VI, with moderate to severe dark circles and under-eye puffiness
Principal investigator: Anna Hardy
Study site: Validated Claim Support, Teaneck, NJ
Study commencement: April 2023
Key test parameters: Expert clinical grading, biophysical instrumentation, subjective user perception, and clinical photography with analysis were all primary data endpoints.
Highlighted results: Tolerability scores showed no increase, a viable marker for topical safety and lack of irritation. Data was collected on dark circles, puffiness, and brightening, with multiple positive outcomes recorded. Final claims are not published by the sponsor.
The Validated difference: VCS's diverse panel pool and photographic capabilities made it possible to recruit a diverse clinical panel with visual endpoints. This study used VISIA CR photography with data analysis to provide clinical and claim substantiation data.
Case study: mineral sunscreen
Johnson & Johnson / Kenvue: Whitening Effect of Mineral Sunscreens on Multi-Cultural Skin Tones
As a leader in global skincare and suncare, J&J set out to show that its mineral sunscreens, which can leave a white cast on deeper skin tones, were less visible than some competitors. For a brand selling to widely diverse populations, Validated Claim Support was the right fit for the study.
Protocol purpose: To evaluate whether six mineral sunscreens caused any visible whitening effect on multi-cultural skin tones (Fitzpatrick IV to VI), and to assess the relationship between self-perceived and objectively measured whitening.
Design: Single-center study at VCS. Each participant was randomly assigned two of six sunscreens for the lower legs, then chose one for the full face. All six were also applied to six forearm sites by a trained designee.
Principal investigator: Anna Hardy
Study site: Validated Claim Support, Teaneck, NJ
Study commencement: December 2021
Key test parameters:
- Objective instrumentation measurements and imaging
- Controlled dosing (2.00 ± 0.05 mg/cm²) applied via tuberculin syringe and finger cot
- Self-assessment questionnaires rating brightness, clarity, and texture on a 1 to 10 satisfaction scale
Highlighted claims:
- None of the six mineral sunscreens caused a visible whitening effect on multi-cultural skin tones
- No significant differences in skin tone were found across the six forearm test sites
- Findings were consistent across self-assessment, instrumentation, and imaging
Outcomes: The study supports that mineral sunscreens can be formulated and validated as safe and cosmetically acceptable across deeper skin tones, addressing the visible white cast that discourages sunscreen reapplication in these populations.
The Validated difference: The study shows the importance of inclusive testing beyond the lighter Fitzpatrick types typically used in standard SPF testing. It drew on VCS's photography studio techniques for capturing complex body care images across varied skin tones, and VCS was selected because its participant database in Teaneck, NJ covers Fitzpatrick types IV through VI.
Case study: hyperpigmentation
Good Molecules: An 18-Week Study of a Test Product With a Marketed Prescription Product
Good Molecules is a skincare brand developed around the in-house needs of online beauty retailer Beautylish. Its formulations use research-backed ingredients for concerns like acne, redness, and hyperpigmentation. Good Molecules relies on strong clinical study designs to support its label claims, and its long-term relationship with Validated Claim Support provides that pathway.
Protocol purpose: To assess the efficacy of a topical test product, used alongside a marketed prescription treatment, in improving skin lightness, hyperpigmentation (dark spots), brightness and radiance, and skin texture over 18 weeks. The data is intended to support Good Molecules' marketing claims.
Participants: Women of any race, ages 18 to 75, with facial hyperpigmentation and/or melasma
Principal investigator: Anna Hardy
Study site: Validated Claim Support, Teaneck, NJ
Study commencement: September 2025
Key test parameters:
- Participants used a generic 4% hydroquinone prescription cream for up to 10 weeks of the study
- Participants used no other hyperpigmentation treatments outside the protocol (prescription drug, test product, and SPF 50 only)
- The study measures skin lightness, hyperpigmentation, brightness and radiance, and texture
Highlighted claims: Facial hyperpigmentation, facial skin texture, facial brightness and radiance, and visual changes via clinical photography.
Outcomes: This completed Phase 3 study evaluated a Good Molecules topical product used alongside a standard-of-care hydroquinone prescription for melasma and facial hyperpigmentation, tracking skin lightness, brightness, radiance, and texture over 18 weeks. It supports Good Molecules' approach of pairing over-the-counter formulations with dermatologist-standard treatments to back substantiated efficacy claims.
The Validated difference: VCS's participant database with facial hyperpigmentation and melasma, and its long-term relationship with Allendale Investigational IRB, provided a viable path to data collection. Consultations with the VCS clinical team produced a study design with high-end clinical photography to show efficacy directly to consumers.
Expert Clinical Grading
Trained graders score visible changeSupports claims like “Clinically proven to reduce the appearance of fine lines and wrinkles”
Learn more →Biomarkers and Microbiome
Tape strips, swabs and collectionsSupports claims like “Microbiome friendly” and “Won’t disrupt the skin’s natural microbiome”
Learn more →Biophysical Instrumentation
Hydration, TEWL, elasticity, colorSupports claims like “Hydrates by up to 87% in as little as one use”
Learn more →Peer-Reviewed Writing
Clinical and scientific publicationsScientifically validated study summaries for publication in peer-reviewed medical journals
Learn more →Before and After Photography
Controlled, reproducible clinical imagingSupports claims like “Up to a 44% reduction in redness in as little as 2 weeks”
Learn more →Consumer Perception
Panelist questionnaires and self-assessmentSupports claims such as “97% of women agreed their skin felt smoother and more supple”
Learn more →Become One of Our Case Studies
If you would like your published results featured here, or you are planning a study you may want to publish, our business development team would be glad to talk.
